Genetics of healthy ageing (PhD ceremony)

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26 May 12:45 hr Doopsgezinde Kerk

PhD ceremony: Ms S. (Sylwia) Figarska
When: May 26, 2014 
Start: 12:45
Promotor: prof. dr. H.M. (Marike) Boezen
Where: Doopsgezinde Kerk
Faculty: Medical Sciences / UMCG

Ageing is defined as a decline of physiological functions. Decline of physiological functions ultimately lead to the development of age-related diseases, such a cardiovascular disease (CVD) or Chronic Obstructive Pulmonary Disease (COPD), and in consequence to death. Humans age at different pace; they develop a disease and die at different ages. Among factors influencing human lifespan, genetics seem to play an important role, since the variation in human lifespan is heritable for approximately 30%. This thesis focuses on the genetic factors influencing human all-cause and cause-specific mortality, i.e. cardiovascular and COPD mortality in the general population.